Protein Losing Enteropathy after Fontan Surgery – Clinical and Diagnostical Aspects
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چکیده
منابع مشابه
Protein Losing Enteropathy after Fontan Surgery – Clinical and Diagnostical Aspects
Protein losing enteropathy (PLE) is the massive enteric loss of serum protein. PLE may appear in several diseases associated with intestinal mucous membrane damages with or without infection. PLE is mostly associated with total cavopulmonary connection (TCPC) or Fontan-type circulation in patients with a functionally univentricular heart. TCPC is performed at an age of about 2 years or older an...
متن کاملProtein-losing enteropathy after the Fontan operation.
Patients were observed after the Fontan operation to determine the frequency and severity of protein-losing enteropathy. A total of 427 patients who survived for 30 days after the Fontan operation, performed between 1973 and January 1987, were analyzed and, thus far, protein-losing enteropathy has developed in 47 of 427. The cumulative risk for the development of protein-losing enteropathy by 1...
متن کاملClinical outcomes and improved survival in patients with protein-losing enteropathy after the Fontan operation.
BACKGROUND Patients with protein-losing enteropathy (PLE) following the Fontan operation have a reported 50% mortality at 5 years after diagnosis. OBJECTIVES The aim of this study was to review outcomes in patients with PLE following the Fontan operation. METHODS From 1992 to 2010, 42 patients (55% male) with PLE following the Fontan operation were identified from clinical databases at the ...
متن کاملProtein-losing enteropathy after fontan surgery: is assessment of risk patients with immunological data possible?
BACKGROUND Protein-losing enteropathy (PLE) is a late complication of the Fontan type surgery for univentricular heart characterized by massive enteric protein loss. The pathogenesis of PLE is not fully understood, and it is unclear why the onset of PLE varies widely and occurs months or even years after surgery. Besides characteristic laboratory findings, a typical cellular feature concerns th...
متن کاملProtein-losing enteropathy after the Fontan operation: clinical analysis of nine cases.
BACKGROUND Protein-losing enteropathy (PLE) is a serious complication of a Fontan operation and has a very high mortality rate. The purpose of this study was to investigate the incidence, clinical manifestations, diagnostic approaches, laboratory findings, therapeutic modalities and outcome of patients with PLE at our institution. METHODS The diagnosis of PLE was based on clinical manifestati...
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ژورنال
عنوان ژورنال: Transfusion Medicine and Hemotherapy
سال: 2007
ISSN: 1660-3796,1660-3818
DOI: 10.1159/000101373